"Women have been most affected by the collapse of the local economy and have since organized themselves in small groups to offer advice to one another, working together to resolve family and community conflicts" (FoE 2012). This paper examines gender-based impacts of commercial oil palm in Bugala island, Kalangala district, where large scale oil palm development is ongoing, and informs on a similar forthcoming project in Buvuma. Findings are based on a literature review, viewed through the five dimensions (land rights, productive resource, household labour, employment and decision making) of an analytical framework for gender impacts of foreign investment in agriculture, and provides information on the impacts of oil palm on social and gender related issues including HIV. The outcomes of agricultural investments for men and women often differ in rural areas where gender inequalities are persistent. Barriers to women's access to productive resources such as production inputs, credit and training reduce female agricultural producers' yields by 20-30% from their full potential. Oil palm has taken over the landscape, altering women's relationship with the forest as opportunities such as handicrafts production have gone. The reduction in local food supply has meant more food has to be imported, leading to increased food prices and more malnutrition among children. In summary, there was 'gender blindness' and a lack of gender sensitive analysis of the impacts of large land deals on land ownership, accessibility, and disempowerment of women and girls thereby reinforcing the existing gender inequality. Also, that although the oil palm project is promoted as a poverty-reducing endeavour, it has caused displacement, food insecurity and deforestation all these affect the mostly women, children and other disadvantaged groups. Thus, with oil palm expansion in Kalangala, local communities lose out to the interests of corporate capital.